CLL Global Research Foundation is currently accepting Letters of Intent (LOI)
through 5:00 PM CT on Friday, May 23, 2025. Click the Letter of Intent box for
submission guidelines and the application form.

If you intend to submit an LOI, please notify Sam Pace by email at mcpace@cllglobal.org and include the research priority your application will address.

Research Priorities

The CLL Global Scientific Advisory Board has outlined the following research priorities.
Letters of intent should address at least one of these.

1. BTK and BCL-2 Inhibitor Refractory Disease
   Investigate mechanisms of resistance and explore novel strategies to overcome
   refractory disease.
2. Richter Transformation
   Advance our understanding of the biology, diagnosis, and treatment of Richter
   transformation.
3. Immune Dysfunction and Restoration
   Examine the causes of immune dysregulation in CLL and develop approaches to
   restore immune function.
4. Novel Therapeutic Targets and Approaches
   Identify and validate new molecular targets and innovative treatment strategies
   for CLL.